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Genetic analysis of Thailand hantavirus in Bandicota indica trapped in Thailand

Abstract : Sixty one tissue samples from several rodent species trapped in five provinces of Thailand were examined for the presence of hantaviral markers by enzyme-immunoassay and immunoblotting. Four samples, all from the great bandicoot rat Bandicota indica, were confirmed positive for the hantaviral N-antigen. Two of them were trapped in Nakhon Pathom province, the other two in Nakhon Ratchasima province, approximately 250 km from the other trapping site. When analysed by RT-nested PCR, all four rodents were found positive for the hantaviral S- and M-segment nucleotide sequences. Genetic analysis revealed that the four newly described wild-type strains belong to Thailand hantavirus. On the phylogenetic trees they formed a well-supported cluster within the group of Murinae-associated hantaviruses and shared a recent common ancestor with Seoul virus.
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Jean-Pierre Hugot, Angelina Plyusnina, Vincent Herbreteau, Kirill Nemirov, Juha Laakkonen, et al.. Genetic analysis of Thailand hantavirus in Bandicota indica trapped in Thailand. Virology Journal, BioMed Central, 2006, 3, pp.NIL_1-NIL_9. ⟨10.1186/1743-422X-3-72⟩. ⟨ird-00380483⟩



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