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Terahertz biomems for enzymatic catalysis monitoring

Abstract : This work focuses on the fabrication and use of a Biological Micro-ElectroMechanical System (BioMEMS) for TeraHertz (THz) detection and characterization of enzymatic catalysis reactions. The fluidic microdevice was fabricated using traditional lithographic techniques. It was then functionalized by reactive amine functions using plasma polymerized allylamine (pp-allylamine), followed by enzyme immobilization inside the microchannels. The enzymatic reaction was controlled by fluorescent microscopy before being analysed by sub-THz spectroscopy in the frequency range 0.06–0.11 THz. The preliminary results show the feasibility of terahertz monitoring of the biocatalysis reaction.
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Contributor : Abdennour Abbas Connect in order to contact the contributor
Submitted on : Wednesday, June 24, 2009 - 1:13:48 PM
Last modification on : Tuesday, November 22, 2022 - 2:26:14 PM
Long-term archiving on: : Tuesday, June 15, 2010 - 6:19:00 PM


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  • HAL Id : ird-00397688, version 1
  • ARXIV : 0907.1162



Abdennour Abbas, A. Treizebre, Nour Eddine Bourzgui, Didier Guillochon, Dominique Vercaigne-Marko, et al.. Terahertz biomems for enzymatic catalysis monitoring. 5th International Conference on Microtechnologies in Medicine and Biology, Jun 2009, Québec City, Canada. pp.214-215. ⟨ird-00397688⟩



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